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目的:探讨前列通对实验性前列腺增生的治疗作用。方法:利用大鼠和小鼠的前列腺增生模型及兔离体膀胱三角肌标本,观察分析前列通的抗前列腺增生作用和机理。结果:每日给前列通3g/kg及6g/kg灌胃,连续3~4周可分别显著抑制丙酸睾丸素引起的大鼠前列腺增生和小鼠尿生殖窦植入性前列腺增生;0.6%及1%前列通水混悬液尚可抑制去甲肾上腺素诱发的兔离体膀胱三角肌收缩作用,抑制率分别达21%及46.1%。结论:前列通具有显著抑制前列腺增生的作用和对抗α受体激动剂诱发的膀胱三角肌收缩的作用
Objective: To explore Qianlie Tong on the experimental treatment of benign prostatic hyperplasia. Methods: Prostate hyperplasia in rats and mice and prostatic hyperplasia in rabbits were observed and analyzed. Results: Ginsenoside 3g / kg and 6g / kg gavage daily for 3 ~ 4 weeks significantly inhibited testosterone propionate-induced rat prostatic hyperplasia and mouse genitourinary sinus implanted prostatic hyperplasia; 6% and 1% forefront of the water suspension can inhibit norepinephrine-induced contraction of the bladder in vitro deltoid muscle, the inhibition rates were 21% and 46.1%. Conclusion: Qianlietong has a significant inhibitory effect on prostatic hyperplasia and antagonism of α receptor agonist-induced bladder deltoid contraction