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目的 :探讨血清 型胶原 ( CIV)在丙型肝炎中的临床意义。方法 :采用放射免疫法 ( RIA)分别检测 89例丙型肝炎及 77例乙型肝炎患者的 CIV值并与正常人 2 0例对照。结果 :丙型肝炎、乙型肝炎患者血清 型胶原值均明显高于正常对照组 ( P<0 .0 1) ;临床不同病期的丙型肝炎患者血清 型胶原值亦均明显高于乙型肝炎组 ( P<0 .0 1)。结论 :丙型肝炎易于慢性化 ,易于发展为肝硬化
Objective: To investigate the clinical significance of serum type collagen (CIV) in hepatitis C virus. Methods: The CIV values of 89 patients with hepatitis C and 77 patients with hepatitis B were detected by radioimmunoassay (RIA) and compared with 20 normal subjects. Results: Serum collagen of patients with hepatitis C and hepatitis B were significantly higher than that of the control group (P <0.01). Serum collagen values of patients with hepatitis C at different stages were also significantly higher than those of patients with type B Hepatitis group (P <0.01). Conclusion: Hepatitis C is easy to be chronic and easy to develop into cirrhosis