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目的观察奥美拉唑与伊托必利联合治疗反流性食管炎的效果。方法回顾性分析2013年1月—2015年6月收治的反流性食管炎80例患者临床资料,按治疗所用方法分为两组,对照组34例患者行单药奥美拉唑治疗,观察组46例患者行奥美拉唑与伊托必利联合治疗,对比两组疗效与症状评分情况。结果观察组总有效率高于对照组,差异有统计学意义(P<0.05);两组治疗后症状(反流、反酸、胸骨后疼痛)评分均较治疗前改善,差异有统计学意义(P<0.05);治疗后观察组各症状评分结果均好于对照组,差异均有统计学意义(P<0.05)。结论反流性食管炎患者行奥美拉唑与伊托必利联合治疗效果较好,值得推广。
Objective To observe the effect of omeprazole and itopride in the treatment of reflux esophagitis. Methods The clinical data of 80 patients with reflux esophagitis admitted from January 2013 to June 2015 were retrospectively analyzed. According to the method of treatment, they were divided into two groups. In the control group, 34 patients were treated with omeprazole alone. Group 46 patients omeprazole and itopride combined treatment, the two groups were compared efficacy and symptom score. Results The total effective rate in the observation group was higher than that in the control group (P <0.05). The scores of symptoms (reflux, acid reflux and post-sternum pain) in both groups were improved after treatment, with significant difference (P <0.05). After treatment, the score of each symptom score in the observation group was better than that in the control group, with significant difference (P <0.05). Conclusion Reflux esophagitis in patients with omeprazole and itopride combined treatment is better, it is worth promoting.