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目的探讨甘精胰岛素联合那格列奈治疗老年2型糖尿病的可行性及优势。方法回顾性分析2008年1月至2009年1月应用甘精胰岛素联合那格列奈治疗老年2型糖尿病10例的临床资料。结果10例患者中有7例患者应用甘精胰岛素联合那格列奈后疗效满意,另3例因血糖控制不佳而联合应用短效胰岛素治疗后血糖控制满意。7例患者应用甘精胰岛素联合那格列奈后无低血糖症状发生。结论甘精胰岛素联合那格列奈治疗用于老年2型糖尿病患者是一种安全有效且方便的治疗方案,低血糖发生的可能性小,对于部分认知程度不佳活动能力较差或合并多种慢性疾病的老年患者,本方案可考虑应用。
Objective To investigate the feasibility and advantages of glargine combined with nateglinide in the treatment of type 2 diabetes in the elderly. Methods The clinical data of 10 patients with type 2 diabetes mellitus treated with glargine and nateglinide from January 2008 to January 2009 were retrospectively analyzed. Results Seven of 10 patients were satisfied with glargine and nateglinide, and the other 3 patients were satisfied with glycemic control after short-acting insulin treatment because of poor control of blood glucose. Seven patients had no symptoms of hypoglycaemia with glargine and nateglinide. Conclusion Glargine combined with nateglinide is a safe, effective and convenient treatment for elderly patients with type 2 diabetes. The likelihood of hypoglycemia is low, and it may be less effective or partially combined for poor cognition The elderly patients with chronic diseases, the program can be considered for application.