妇女月经周期过程中类固醇激素对血清钙和镁离子水平的调节

• 作 者: 郭虹
• 出 处: 国外医学(计划生育分册)
• 发表日期: 1999年02期
• 关键词: 类固醇激素 妇女月经 经前期综合征 神经肌肉 口服避孕药 心血管疾病 骨代谢 血清浓度 血清钙 周期过程

二价镁(Mg~(2+))和钙(Ca~(2+))阳离子影响经前期症状的出现如经前期偏头痛;经前期综合征(PMS);孕期疾病(预痫和子痫);更年期心血管疾病;骨病(骨的丢失和骨折的易感性);及口服避孕药后的病生理。这两种离子亦参与中间代谢、神经肌肉活动、刺激分泌、血管紧张性及骨代谢等活动。而这些活动均由各种激素,包括性腺类固醇激素来调节。为了解月经周期不同阶段类固醇激素的血清浓度及其对应阶段的生物活性的血清Ca~(2+)、Mg~(2+)离子浓度之间的关系,及Ca~(2+)/Mg~(2+)比

Magnesium divalent (Mg 2+) and calcium (Ca 2+) cations influence the development of premenstrual symptoms such as premenstrual migraines; premenstrual syndrome (PMS); prenatal diseases (pre-eclampsia and eclampsia) ; Menopausal cardiovascular disease; bone disease (loss of bone and susceptibility to fractures); and disease physiology after oral contraceptives. These two ions are also involved in intermediate metabolism, neuromuscular activity, stimulating secretion, vascular tone and bone metabolism and other activities. These activities are regulated by various hormones, including gonadal hormones. In order to understand the relationship between serum concentrations of Ca ~ (2 +) and Mg ~ (2+) and serum levels of Ca ~ (2 +) / Mg ~ (2+) in different phases of menstrual cycle, (2+) ratio