Genetic Variants in EGFR/PLCE1 Pathway Are Associated with Prognosis of Esophageal Squamous Cell Car

• 作 者: Yu-li WANG Ye YUAN Xiao-xiao L
• 机 构: DepartmentofOncology,DepartmentofClinicalMedicine,DepartmentofOncology
• 出 处: 当代医学科学(英文)
• 发表日期: 2019年3期
• 关键词: ESOPHAGEAL SQUAMOUS cell carcinoma PROGNOSIS single NUCLEOTIDE polymorphism surv
• 基金项目: This work was supported by the Double First-Class Construction Project(No.540-5001540067),the Construction of Information Resources Database in Tumor Multi-omics and Multi-beam Project (No.2016YFC0904

Esophageal cancer (EC) is one of the most deadly malignant diseases. Several studies revealed that variations of the phospholipase C epsilon 1 (PLCE1) gene were associated with EC susceptibility. PLCE1 is located downstream of the epidermal growth factor