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光动力学治疗(PDT)是一种新的内镜下局部治疗肿瘤的方法。新的内源性光致敏剂氨基乙酰丙酸(ALA:Aminolaevulinsure)治疗重度不典型增生的Barrett食管或表浅鳞癌具较高粘膜特异性,且对皮肤无毒性反应,将来可能成为手术高危病人的另一治疗选择。 原理和方法 PDT的原理是口服光致敏剂,利用其选择性蓄积于肿瘤组织的特性,内镜下用激光
Photodynamic therapy (PDT) is a new method of endoscopic treatment of tumors. The new endogenous photosensitizer ALA: Alanolaevulinsure is highly mucosal specific for severe dysplasia of Barrett’s esophagus or superficial squamous cell carcinoma and has no toxic reaction to skin and may become a surgical risk in the future Another treatment option for the patient. Principles and methods The principle of PDT is oral photosensitizer, which uses its selective accumulation in the characteristics of the tumor tissue, using laser under the endoscope.