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目的观察沙丁胺醇结合酮替芬用于治疗小儿哮喘的效果。方法 96例小儿哮喘患儿,随机分为对照组和实验组,各48例。对照组采用临床常规的综合性治疗方法 ,实验组采用沙丁胺醇联合酮替芬进行治疗,比较两组患儿治疗效果和各项临床表现(咳嗽、气促、肺部湿啰音)消退时间。结果实验组患儿总有效率为93.75%,明显高于对照组的75.00%,差异有统计学意义(P<0.05)。对照组咳嗽消退时间为(9.14±2.21)d,气促消退时间为(4.37±1.26)d,肺部湿啰音消退时间为(7.28±2.26)d;实验组咳嗽消退时间为(6.34±1.52)d,气促消退时间为(2.34±0.78)d,肺部湿啰音消退时间为(4.38±1.12)d;实验组患儿咳嗽、气促以及肺部湿啰音消退时间均明显短于对照组,差异有统计学意义(P<0.05)。结论对于小儿哮喘患儿采用沙丁胺醇结合酮替芬的治疗效果更为显著,可有效缩短咳嗽、气促以及肺部湿啰音的时间,利于患儿病情恢复,值得临床推广。
Objective To observe the effect of albuterol combined with ketotifen for the treatment of pediatric asthma. Methods 96 pediatric children with asthma were randomly divided into control group and experimental group, 48 cases each. The control group was treated with routine clinical comprehensive treatment. The experimental group was treated with salbutamol combined with ketotifen. The therapeutic effect and the clinical manifestations (cough, shortness of breath, lung wet rales) of two groups were compared. Results The total effective rate of the experimental group was 93.75%, which was significantly higher than that of the control group (75.00%), the difference was statistically significant (P <0.05). The cough subsided time was (9.14 ± 2.21) d in the control group, (4.37 ± 1.26) d and the pulmonary wet rales subsided time was (7.28 ± 2.26) days respectively. The cough subsided time in the experimental group was (6.34 ± 1.52) ), d (2. 34 ± 0. 78) d and (4.38 ± 1.12) d of lung wet rales. The cough, shortness of breath and lung wet rales in the experimental group were significantly shorter than those in the experimental group Control group, the difference was statistically significant (P <0.05). Conclusion The treatment effect of salbutamol combined with ketotifen in children with asthma is more significant, which can effectively shorten the cough, shortness of breath and the time of pulmonary wet rales, which is beneficial to the recovery of children’s condition and worthy of clinical promotion.