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目的研究甲泼尼松龙联合阿奇霉素治疗小儿难治性支原体肺炎的临床疗效。方法 120例小儿难治性支原体肺炎患儿为研究对象,将其随机分为观察组和对照组,每组60例。对照组单采用阿奇霉素治疗,观察组在使用阿奇霉素的基础上再加上甲泼尼松龙治疗,对比两组疗效。结果观察组患儿显效30例、有效25例、无效5例,总有效率为91.67%;对照组患儿显效8例、有效20例、无效32例,总有效率为46.67%;观察组患儿治疗的总有效率明显高于对照组,差异具有统计学意义(χ~2=28.486,P<0.05)。结论甲泼尼松龙联合阿奇霉素治疗小儿难治性支原体肺炎的疗效确切,此联合用法可作为治疗小儿难治性支原体肺炎的首选方法。
Objective To study the clinical efficacy of methylprednisolone combined with azithromycin in the treatment of refractory mycoplasma pneumonia in children. Methods A total of 120 children with refractory mycoplasma pneumonia were enrolled in this study. They were randomly divided into observation group and control group, 60 cases in each group. The control group alone treated with azithromycin, the observation group on the basis of the use of azithromycin plus methylprednisolone treatment, the two groups were compared. Results In the observation group, 30 cases were markedly effective, 25 cases were effective, 5 cases were ineffective, and the total effective rate was 91.67%. In the control group, 8 cases were markedly effective, 20 cases were effective and 32 cases were ineffective. The total effective rate was 46.67% The total effective rate of treatment of children was significantly higher than that of the control group, the difference was statistically significant (χ ~ 2 = 28.486, P <0.05). Conclusion The combination of methylprednisolone and azithromycin is effective in the treatment of refractory mycoplasma pneumonia in children. This combination can be the first choice for the treatment of refractory mycoplasma pneumonia in children.