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目的:探讨2型糖尿病患者窦性心率震荡现象及与心率变异指标的相关性。方法:2型糖尿病患者70例(糖尿病组),健康对照者40例(对照组)均行24 h动态心电图检查,计算并比较2组心率震荡初始、震荡斜率2、4 h正常窦性心律RR间期标准差、24 h每5 min窦性RR间期平均值的标准差、全程相邻RR间期之差的均方根值及其相关性。结果:2组各指标比较差异均有统计学意义(P<0.05);糖尿病组震荡初始与4 h正常窦性心律RR间期标准差、24 h每5 min窦性RR间期平均值的标准差、全程相邻RR间期之差的均方根值呈负相关,震荡斜率与4 h正常窦性心律RR间期标准差、24 h每5 min窦性RR间期平均值的标准差、全程相邻RR间期之差的均方根值呈正相关,震荡初始与震荡斜率无相关性。结论:2型糖尿病患者室性早搏后的窦性心率震荡现象减弱,心率振荡可成为评价2型糖尿病患者自主神经功能的指标。
Objective: To explore the relationship between sinus rhythm of heart rate variability and heart rate variability in patients with type 2 diabetes mellitus. Methods: 70 patients with type 2 diabetes mellitus (DM group) and 40 healthy controls (control group) underwent 24 h ambulatory electrocardiogram examination. The initial sinus rhythm was calculated and compared. The normal sinus rhythm RR Standard deviation of interventricular septum, standard deviation of mean sinus RR interval of 24 h every 5 min, root mean square value of the difference between adjacent RR intervals and their correlation. Results: There were significant differences in each index between the two groups (P <0.05). The standard deviation of RR of sinus rhythm between initial diastole and normal sinus rhythm at 4 h and the standard of sinus RR interval at 5 min after 24 h The rms values of the difference between the adjacent RR intervals were negatively correlated with the standard deviation of the rhythm of slope and the standard deviation of 4 h normal sinus rhythm RR intervals and the average of sinus RR intervals of 24 h every 5 min, The root mean square of the difference between adjacent RR intervals was positively correlated, but there was no correlation between the initial oscillation and the slope of oscillation. CONCLUSION: The sinus rhythm of ventricular premature beats in type 2 diabetic patients is weakened. Heart rate oscillation may be an index to evaluate the autonomic nervous function in type 2 diabetic patients.