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妊娠对结核病预后的影响自中世纪至19世纪初期,不少临床家认为妊娠对结核病有良好影响,因增大的子宫压迫肺脏,可使开放的空洞塌陷。至19世纪中叶又有人指出妊娠对结核病有不良影响,结核病可致流产,妊娠也可使结核病播散。Hedvall’s研究了胸片示有结核病表现的250例妇女,妊娠期间改善者9%,恶化7%,其余84%保持不变;产后第1年76%病变仍稳定,15.2%恶化,8.8%改善,说明病情恶化与喂奶无明显关系,但产后第1年病变活动的危险性较大。Crombie的观察也支持这看法,在110例非活动性结核病的妊娠妇女,产后31例复发,其中20例出现在产后第1年,这可能与内分泌的急剧变化、产后横膈降低、哺乳致营养缺乏、睡眠不足等因
The impact of pregnancy on the prognosis of tuberculosis From the Middle Ages to the early 19th century, many clinicians believe that pregnancy has a good impact on tuberculosis, because the enlarged uterus oppression of the lungs, can open the hollow collapse. By the mid-19th century, some people pointed out that pregnancy has an adverse effect on tuberculosis, tuberculosis can cause miscarriage and pregnancy can also cause the spread of tuberculosis. Hedvall’s studied 250 cases of chest X-ray manifestations of tuberculosis, improved 9% during pregnancy, worsening of 7%, the remaining 84% remained unchanged; 76% of the first year postpartum disease was stable, 15.2% deteriorated, 8.8% improvement, Shows that the deterioration of the disease and no significant relationship between breast feeding, but the first year postpartum greater risk of disease activity. Crombie’s observation also supports this belief: in 110 pregnant women with inactive TB, 31 have been relapsed after delivery, 20 of which occur in the first year of childbirth, which may be related to the dramatic changes in endocrine, postpartum diaphragmatic reduction, and lactation to nutrition Lack, lack of sleep and other reasons