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目的观察临床分离大肠埃希菌耐药情况,为临床合理使用抗菌药物提供依据。方法采用细菌分离和鉴定方法及药敏试验方法,对某医院临床标本中分离的507株大肠埃希菌的耐药情况进行了观察。结果该医院临床标本分离的大肠埃希菌对多种常用抗菌药物耐药率较高,对厄他培南、亚胺培南、头孢替坦、丁胺卡那等抗菌药物较敏感,对美洛培南敏感率100%。结论临床分离的大肠埃希菌对常用抗菌药物耐药率高,应提高药敏试验率,以便合理使用抗菌药物。
Objective To observe the drug resistance of Escherichia coli isolated clinically and provide basis for the rational use of antibacterials in clinic. Methods Bacterial isolation and identification methods and susceptibility testing methods were used to detect the resistance of 507 Escherichia coli isolated from clinical specimens in a hospital. Results The Escherichia coli isolated from clinical specimens of this hospital showed a high resistance rate to various commonly used antibiotics and was more sensitive to the antibiotics such as ertapenem, imipenem, cefotetan, and amikacin, Luo Pei Nan sensitivity rate of 100%. Conclusion The clinical isolates of Escherichia coli commonly used antimicrobial resistance rate is high, should increase the susceptibility testing rate, in order to rational use of antimicrobial agents.