论文部分内容阅读
目的:研究赤芍组分SY-002对大鼠子宫肌瘤的治疗作用。方法:以雌激素和孕酮联合诱导大鼠子宫肌瘤为模型,设正常对照组、模型组、赤芍组分SY-002低(10 mg·kg~(-1)·d~(-1))、赤芍组分SY-002中(30 mg·kg~(-1)·d~(-1))、赤芍组分SY-002剂量高三个剂量组(100 mg·kg~(-1)·d~(-1)),灌胃给药,2次/d;以子宫系数、病理形态学、子宫平滑肌厚度、血清中雌激素、孕酮含量为观察指标。结果:赤芍组分SY-002对子宫肌瘤有明显抑制作用,病理形态学改善作用明显,对血清雌激素均有不同程度的抑制作用。结论:赤芍组分SY-002对子宫肌瘤具有一定的治疗作用。
Objective: To study the curative effect of TP-SY-002 on uterine fibroids in rats. Methods: Uterine fibroids induced by estrogen and progesterone were used as models. The normal control group, model group and TP group were treated with SY-002 low (10 mg · kg -1 · d -1 ), TP-SY-002 (30 mg · kg -1 · d -1) and TP-SY-002 (100 mg · kg -1) 1) · d ~ (-1)), intragastric administration, 2 times / d; Uterine coefficient, pathomorphology, uterine smooth muscle thickness, serum estrogen and progesterone levels were observed. Results: SY-002 showed obvious inhibitory effect on uterine fibroids, obvious effect on pathomorphology, and inhibitory effect on serum estrogen to some extent. Conclusion: TP-SY-002 has a certain therapeutic effect on uterine fibroids.