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铝有抑止石英的作用,Denny于1937年首先通过家兔实验证明。随后Naesland用豚鼠,King用大白鼠进一步证明金属铝粉确有抑止石英的纤维化作用。此后的研究证明,金属铝粉的吸入只能使矽肺的纤维化延缓,停止吸入铝粉以后则纤维化继续进行。且单纯吸入大量铝粉亦能产生明显的成纤维作用。因而此种疗法虽在某些国家一度被应用,但不久即被否定。 Gardner等人通过给家兔和豚鼠静脉注入和气管吸入实验证实氢氧化铝胶体有抑制石
Aluminum has the role of inhibiting quartz, Denny first in 1937 by rabbit experiments proved. Subsequently, Naesland used guinea pigs, King with rats further evidence that metal aluminum does have a suppressive effect on quartz fibrosis. Subsequent studies have shown that inhalation of metallic aluminum can only delay the fibrosis of the silicosis, and continue fibrosis after inhalation of aluminum powder. And a large number of pure aluminum powder inhalation can produce significant fibroblasts. Therefore, although this kind of therapy was used in some countries for a time, it was soon denied. Gardner et al. By intravenous injection into rabbits and guinea pigs and tracheal aspiration experiments confirmed that the aluminum hydroxide colloid inhibition of stone