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β-2微球蛋白(Beta-2microglobulin),简称β-2m是一种低分子量的蛋白质(分子量11,800Daltons),最早从肾小管受损的患者尿液中得到分离。β-2m是HLA抗原的组成部分,酷似IgG的轻链。有报导,在正常成人血清可测及微量的β-2m。在肾小球疾病,严重的血液系统及其他恶性疾病患者,其值升高。正常妊娠时,母体血清的β-2m水平随妊娠月份增加而升高。近来的研究着眼于测定妊毒症时的β-2m含量。作者采用Anderson和Kelly介绍的ELISA方法,为293例妊娠6～41周健康孕妇,73例妊娠末三月先兆子痫孕妇作血清β-2m测定。293例健康孕
β-2 microglobulin (Beta-2 microglobulin), referred to as β-2m is a low-molecular-weight protein (molecular weight 11,800 Daltons), the earliest from the renal tubular lesions were isolated urine. β-2m is an integral part of an HLA antigen that resembles the light chain of IgG. It has been reported that in normal adult serum measurable trace β-2m. In glomerular disease, severe hematological system and other malignant diseases, its value increased. In normal pregnancy, maternal serum β-2m levels increased with the increase in the month of pregnancy. Recent studies have focused on the determination of β-2m levels in the case of pregnancy. The authors used Anderson and Kelly introduced the ELISA method for 293 healthy pregnant women 6 to 41 weeks pregnant women, 73 pregnant women with preeclampsia at the end of March pregnancy serum β-2m determination. 293 healthy pregnant