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1968年Berger氏和Hinglais氏首次叙述了IgA肾病。随后发现过敏性紫癜、肝硬化等许多疾病亦可引起肾小球系膜的IgA沉积,故目前将IgA肾病称之谓IgA肾病综合征。近年来此征发病率显著提高,在美国、英国等某些欧美国家已引起小流行,普遍地认识到IgA肾病是肾小球肾炎最常见类型之一。临床病理特点原发性IgA肾病的特点是系膜区IgA沉积,且常伴有C_3、IgG、IgM和纤维蛋白原的沉积,系膜区肿胀伴有不同程度的急性增生性和节段性硬化病灶,系
1968 Berger and Hinglais’s first narrative of IgA nephropathy. Subsequently found that allergic purpura, cirrhosis and many other diseases can also cause glomerular mesangial IgA deposition, it is now called IgA nephropathy that IgA nephrotic syndrome. In recent years, the incidence of this disease significantly increased in some countries such as the United States, Britain and other countries have caused a small epidemic, generally recognized that IgA nephropathy is one of the most common types of glomerulonephritis. Clinicopathological Features Primary IgA nephropathy is characterized by IgA deposition in the mesangial area and is often accompanied by the deposition of C_3, IgG, IgM and fibrinogen, swelling of the mesangial area with varying degrees of acute proliferative and segmental sclerosis Lesions, Department