论文部分内容阅读
目的探讨高血糖对急性脑梗死患者预后及功能康复的影响。方法将2006—2008年入院的2319例急性脑梗死患者按照入院血糖水平分为高血糖组(入院血糖水平≥6.12mmol/L)和血糖正常组(入院血糖水平<6.12mmol/L),采用定期随访观察的方法,对两组患者发病90d后的生存状态、神经功能评分(NIHSS、mRS)进行比较和分析。结果高血糖组急性脑梗死发病90d时的病死率(53.73%)高于血糖正常组(46.27%),差别有统计学意义(P<0.05)。在发病90d后仍存活者中,高血糖组功能康复不良(mRS≥2)的比例(28.19%)高于血糖正常组(19.11%),差别有统计学意义(P<0.05)。血糖正常组mRS≥2者的入院血糖水平([5.05±0.58)mmol/L]高于mRS<2者([4.92±0.60)mmol/L],差别有统计学意义(P<0.05)。结论高血糖增加脑梗死患者发病90天时的病死率,同时对其功能恢复也有不利影响。监测血糖水平对估计预后有重要意义。
Objective To investigate the effect of hyperglycemia on prognosis and functional rehabilitation in patients with acute cerebral infarction. Methods 2319 patients with acute cerebral infarction admitted to hospital from 2006 to 2008 were divided into hyperglycemia group (admission glucose level≥6.12mmol / L) and normal blood glucose level (admission glucose level≤6.12mmol / L) Follow-up observation of the two groups of patients 90d after onset of survival status, neurological function score (NIHSS, mRS) were compared and analyzed. Results The mortality of acute cerebral infarction in hyperglycemia group (53.73%) at 90 days was higher than that in normal glucose group (46.27%), the difference was statistically significant (P <0.05). The proportion of dysfunctional (mRS≥2) in hyperglycemia group (28.19%) was higher than that in normal glucose group (19.11%) after 90 days of onset, the difference was statistically significant (P <0.05). The blood glucose level (5.05 ± 0.58 mmol / L) in patients with normal blood glucose and mRS≥2 was higher than those with mRS <2 (4.92 ± 0.60) mmol / L, the difference was statistically significant (P <0.05). Conclusions Hyperglycemia increases the mortality of patients with cerebral infarction at onset of 90 days and also has an adverse effect on their functional recovery. Monitoring blood glucose levels is important for estimating prognosis.