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目的:对慢性心衰(CHF)患者联用硝普钠与多巴胺治疗的效果进评析。方法:将2016年1月~2017年1月我院心内科收治的102例CHF患者纳入观察研究中,通过数字表法随机分成探究组和对比组,各51例,对比组应用常规药物治疗,探究组同时联用硝普钠、多巴胺治疗,连续治疗7d,对比分析两组疗效及心功能改善情况。结果:通过治疗后,探究组临床总有效率为94.1%,优于对比组的78.4%,差异有统计意义(P<0.05);治疗前后两组患者的心率(HR)、左室射血分数(LVEF)、左室舒张末直径(LVD)、左室短轴缩短率(LVFS)、心胸比率差异有统计意义(P<0.05);两组治疗中均未出现严重不良反应。结论:对CHF患者在常规治疗同时联用硝普钠和多巴胺治疗效果确切,能有效改善心功能,临床意义重大。
Objective: To evaluate the effect of nitroprusside and dopamine in patients with chronic heart failure (CHF). Methods: From January 2016 to January 2017, 102 CHF patients admitted to our hospital were included in the study. The patients were randomly divided into the exploration group and the control group by digital table method, with 51 cases in each group. The control group was treated with conventional drugs, The study group was treated with sodium nitroprusside and dopamine simultaneously for 7 days. The curative effect and the improvement of cardiac function were compared between the two groups. Results: After treatment, the total clinical effective rate was 94.1% in the study group and 78.4% in the comparison group, the difference was statistically significant (P <0.05); before and after treatment, the heart rate (HR), left ventricular ejection fraction (LVEF), left ventricular end-diastolic diameter (LVD), left ventricular fractional shortening (LVFS), and cardiothoracic ratio had statistical significance (P <0.05). No serious adverse reactions occurred in both groups. CONCLUSIONS: The treatment of CHF patients with sodium nitroprusside and dopamine simultaneously with conventional treatment is effective and effective in improving cardiac function, which is of great clinical significance.