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作者在40多年中对经组织学检查证实而诊断的前列腺癌临床B期患者75例进行了前瞻性研究,这些患者在组织学确诊后至少1年未接受治疗,其中,前列腺癌B_1期病变为29例,B_2期病变为37例,B_3期病变为9例.作者随访前列腺癌B_(1-3)期患者的时间的中位值分别为124、120及96个月,最终行骨盆淋巴结割除非行碘植入者5例,经尿道肿瘤切除术者23例,采用内分泌疗法者18例.结果发现,所有前列腺癌患者都发生肿瘤扩散,其中,前列腺癌B_1期者19例中的18例(95％),B_2期者29例中的26例(90％)及全部4例B_3期(100％)最初都出现局限性扩散,而前列腺癌B_1期者29例中的6例(21％),B_2期者37例中的17例(46％)及B_3期
In more than 40 years, the authors conducted a prospective study of 75 patients with stage B prostate cancer diagnosed by histological examination and who were not treated for at least 1 year after histological diagnosis. Among them, prostate cancer had a B_1 lesion. In 29 patients, there were 37 patients with B_2 lesions and 9 patients with B_3 lesions. The median follow-up time for patients with B_(1-3) prostate cancer was 124, 120, and 96 months, respectively, and the patients were finally treated with pelvic lymph node dissection. Unless there were 5 patients undergoing iodine implantation, 23 patients undergoing transurethral resection, and 18 patients undergoing endocrine therapy. It was found that tumor spread occurred in all patients with prostate cancer. Among them, 18 out of 19 patients with prostate cancer at B stage were included. (95%) Of the 29 patients (29%) in 29 patients (29%) and all 4 patients in the B3 phase (100%), there was a limited spread initially, and 6 out of 29 patients with B1 prostate cancer (21%) ), Of the 37 cases in B2 phase, 17 cases (46%) and B_3 phase