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目前,世界范围内约有5%的人患有糖尿病,糖尿病的患病率正在迅速增加,尤其是在老年人群。据统计,在糖尿病患者中,超过80%的人患有2型糖尿病。因此,从某种程度上讲,糖尿病患者人数的增加直接反映了2型糖尿病的流行情况。既往实验证实,糖尿病与高血糖特异微血管并发症相关。此外,2型糖尿病导致患者大血管并发症的发生风险增加2～4倍,尤其是冠状动脉疾病(CAD)、中风和外周血管疾病。众所周知,心血管疾病(CVD)是糖尿病常见的慢性并发症,到目前为止,也是导致糖尿病患者死亡的首要原因。流行病学调查显示,在2型糖尿病患者中,超过50%的人死于冠状动脉疾病。
Currently, about 5% of people worldwide have diabetes, and the prevalence of diabetes is rapidly increasing, especially in the elderly. According to statistics, more than 80% of people with diabetes have type 2 diabetes. So, to some extent, an increase in the number of people with diabetes directly reflects the prevalence of type 2 diabetes. Previous experiments confirmed that diabetes and hyperglycemia-specific microvascular complications. In addition, type 2 diabetes leads to a 2 to 4-fold increased risk of macrovascular complications in patients, especially coronary artery disease (CAD), stroke and peripheral vascular disease. It is well-known that cardiovascular disease (CVD) is a common chronic complication of diabetes and so far the leading cause of death in people with diabetes. Epidemiological surveys show that more than 50% of people with type 2 diabetes die of coronary artery disease.