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随着原发性直肠癌治疗手段的不断改进,尤其是全直肠系膜切除和新辅助治疗的出现,直肠癌局部复发率显著降低。但由于受到病人曾经接受过的相关治疗的限制,局部复发直肠癌(locally recurrent rectal cancer,LRRC)的治疗一直以来是备受争议的问题。手术是其主要的治疗手段,但仅有少数病人可以获得根治。因此,针对不同治疗史的病人采取合理有效的多学科综合治疗模式是LRRC治疗的重要原则,而综合治疗时机及合理选择已成为目前研究的热点。
With the continuous improvement of the treatment of primary rectal cancer, especially the total mesorectal excision and neoadjuvant therapy, the local recurrence rate of rectal cancer was significantly reduced. However, the treatment of locally recurrent rectal cancer (LRRC) has been a controversial issue due to limitations of therapies that patients have previously received. Surgery is its main treatment, but only a small number of patients can get radical. Therefore, it is an important principle of LRRC to take rational and effective multidisciplinary comprehensive treatment mode for patients with different treatment history. However, comprehensive treatment timing and rational selection have become the hot topics in the current research.