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目的探讨老年冠心病患者应用阿托伐他汀与曲美他嗪治疗的疗效与安全性。方法 130例老年冠心病患者,随机分为研究组与对照组,各65例。两组患者均对症治疗,对照组应用曲美他嗪治疗,研究组在对照组基础上加服阿托伐他们治疗,观察两组疗效。结果研究组总有效率显著高于对照组(93.85%VS 81.54%),差异具有统计学意义(P<0.05)。两组患者均无明显的药物不良反应。结论老年冠心病患者应用阿托伐他汀与曲美他嗪治疗疗效肯定,安全可靠,适于临床应用。
Objective To investigate the efficacy and safety of atorvastatin and trimetazidine in elderly patients with coronary heart disease. Methods 130 elderly patients with coronary heart disease were randomly divided into study group and control group, 65 cases each. Two groups of patients were symptomatic treatment, the control group was treated with trimetazidine, the study group on the basis of the control group plus atorvastatin treatment, the two groups were observed. Results The total effective rate of the study group was significantly higher than that of the control group (93.85% VS 81.54%), the difference was statistically significant (P <0.05). Two groups of patients had no obvious adverse drug reactions. Conclusion The treatment of senile coronary heart disease patients with atorvastatin and trimetazidine certainly, safe and reliable, suitable for clinical application.