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目的:探讨高原地区脑白质疏松症(LA)与血红蛋白(Hb)的相关性。方法:对160例高原地区老年患者根据CT/MRI结果按有无脑白质疏松,分为LA组82例和非LA组78例,按照脑白质疏松严重程度将LA组患者分为4组,行血红蛋白测定。结果:LA组Hb浓度(16.9±4.1)g/L明显高于非LA组(13.8±3.6)g/L,两组比较差异有统计学意义(P<0.01)。LA3组Hb浓度(17.8±1.9)g/L与LA4组Hb浓度(18.5±3.2)g/L明显高于LA1组Hb浓度(14.8±2.1)g/L及LA2组Hb浓度(15.9±2.2)g/L,差异有统计学意义(P<0.05)。结论:Hb水平与老年LA及其严重程度关系密切,高Hb可能为LA的一个独立危险因素。
Objective: To investigate the correlation between leukoaraiosis (LA) and hemoglobin (Hb) in the plateau area. Methods: 160 elderly patients in the plateau were randomly divided into LA group (n = 82) and non-LA group (n = 78) according to the results of CT / MRI. According to the severity of leukoaraiosis, the patients in LA group were divided into 4 groups Hemoglobin determination. Results: The Hb concentration in LA group (16.9 ± 4.1) g / L was significantly higher than that in non-LA group (13.8 ± 3.6) g / L, with significant difference between the two groups (P <0.01). Hb concentration (17.8 ± 1.9) g / L in LA3 group and Hb concentration (18.5 ± 3.2) g / L in LA4 group were significantly higher than those in LA1 group (14.8 ± 2.1) g / L and LA2 group (15.9 ± 2.2) g / L, the difference was statistically significant (P <0.05). Conclusion: The level of Hb is closely related to the severity of LA and its severity. High Hb may be an independent risk factor for LA.