论文部分内容阅读
目的:比较氟桂利嗪与手术治疗对中枢神经系统感染致患者继发难治性癫痫的预后疗效。方法:选取2010年4月—2015年4月间诊治的中枢神经系统感染致继发难治性癫痫患者50例,并将其随机分为观察组和对照组,每组25例;对照组患者给予氟桂利嗪治疗,观察组患者给予手术治疗,比较治疗后两组患者的总有效率和用药期间不良反应的发生率。结果:两组患者治疗后,观察组患者的预后疗效采用Engel分级表评级的百分率优于对照组(P<0.05),治疗的总有效率为88.00%高于对照组为64.00%(P<0.05),不良反应的发生率为20.00%低于对照组为48.00%(P<0.05)。结论:手术治疗对中枢神经系统感染致患者继发难治性癫痫的预后疗效和不良反应的发生率均优于氟桂利嗪。
Objective: To compare the prognosis of refractory epilepsy secondary to flunarizine and surgical treatment of patients with central nervous system infection. Methods: Fifty patients with secondary refractory epilepsy who were diagnosed as CNS infection during the period from April 2010 to April 2015 were selected and randomly divided into observation group and control group, with 25 cases in each group. Patients in the control group were given Flunarizine treatment, observation group patients were given surgical treatment, the two groups were compared after treatment, the total effective rate and the incidence of adverse reactions during the treatment. Results: After treatment, the prognosis of the observation group was higher than that of the control group (P <0.05). The total effective rate was 88.00% in the observation group and 64.00% in the control group (P <0.05) ), The incidence of adverse reactions was 20.00% lower than the control group was 48.00% (P <0.05). Conclusion: Surgical treatment of CNS infection in patients with secondary refractory epilepsy prognosis and adverse reactions were better than flunarizine.