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喉淀粉样瘤是呼吸道的少见病,我科1989年至1993年手术治疗喉淀粉样瘤10例,现结合临床及病理资料加以分析讨论,以期临床医生对该病有进一步的认识。 临床资料 10例喉淀粉样瘤均经病理检查证实,其中男性6例,女性4例;年龄28～60岁,平均47岁。所有男性病人均嗜烟(吸烟指数均大于400)。发病部位:6例发生于声门区,其中3例位于单侧声带,另4例位于声门上区,其中会厌喉面1例,喉室及室带3例,无一例见于声门下区。临床表现:9例病人主诉声嘶,2例诉有咽隐痛或咽异物感;从首发症状出现至就诊时平均间隔达27个月。局部检查喉内可见单个或多发
Aphthous laryngeal amyloidosis is a rare disease of the respiratory tract. Surgical treatment of laryngeal amyloidosis in 10 cases from 1989 to 1993 in our department is now being analyzed and discussed with clinical and pathological data, so that clinicians can get a better understanding of the disease. Clinical data of 10 cases of laryngeal amyloidosis were confirmed by pathological examination, including 6 males and 4 females; aged 28 to 60 years, mean 47 years. All male patients were smokers (smoking index greater than 400). Incidence site: 6 cases occurred in the glottis area, of which 3 cases were located in the unilateral vocal cord, and the other 4 cases were located in supraglottic area, including epistaxis in 1 case of throat, throat and ventricle in 3 cases, none of which were found in the subglottic region. Clinical manifestations: 9 patients complained of hoarseness, 2 cases of vomiting pain or pharyngeal foreign body sensation; from the onset of symptoms until the time of treatment average interval of 27 months. Local inspection of the throat visible single or multiple