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实验证明胸腺素能延长照射动物的活存时间。我们曾用山东莱阳生化制药厂提取的猪胸腺素对900伦照射小鼠进行了观察,证明它有明显的抗放作用。但对其作用机制和合理的给药方法(剂量、时间)等问题均有待深入研究。根据胸腺素有拮抗甲状腺素及促甲状腺素的作用,提示我们有可能借助甲状腺功能的检查间接反映体内胸腺素含量的变化,从而在认识胸腺素-甲状腺素相互作用的基础上探讨胸腺素的抗放作用机制并解决合理给药问题。甲状腺所产生的激素90%以上是甲状腺素(T_4),因此测定血清总T_4的浓度已成为判
Experiments show that thymosin can prolong the survival time of irradiated animals. We have used Shandong Laiyang biochemical pharmaceutical extraction of pig thymosin 900 Lun irradiated mice were observed, it has obvious anti-lethal effect. However, its mechanism of action and reasonable methods of administration (dose, time) and other issues need further study. According to thymosin antagonism of thyroid hormone and thyroid stimulating effect, suggesting that we may use thyroid function tests indirectly reflect the changes in the content of thymosin in vivo, so as to understand the thymosin - thyroid hormone interaction on the basis of thymosin resistance Put the mechanism of action and solve the problem of rational drug delivery. Thyroid hormone produced by more than 90% is thyroxine (T_4), so the determination of the total serum T_4 concentration has become the sentence