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目的探讨乳腺钼靶X线微钙化在彩超检查阴性乳腺疾病诊断中的应用价值。方法选取珠海市妇幼保健院2010年1月-2015年8月术前钼靶发现微钙化的85例患者作为研究对象,且患者均进行X线和高频彩超等检查,并将X线检查微钙化与病理结果进行比较,观察其临床应用价值。结果 85例患者中良性病变45例(主要包括乳腺病25例,乳腺纤维腺瘤15例,导管上皮不典型增生5例),所占比例为52.9%。恶性病变40例(主要包括浸润性导管癌20例,导管原位癌12例,小叶原位癌5例,浸润性小叶原位癌3例),所占比例为47.1%。乳腺恶性病变簇状钙化与良性病变簇状钙化在钙化数量、钙化点数、钙化密度、每个成簇钙化中钙化颗粒数和钙化病灶直径以及钙化病灶直径与钙化颗粒大小及密度是否均匀方面比较差异有统计学意义(P<0.05)。结论临床中应用乳腺钼靶X线检查微钙化对彩超检查阴性早期乳腺癌的诊断具有较好的应用效果,尤其微钙化在良性病变与恶性病变中的钙化数量、钙化点数、钙化密度、每个成簇钙化中钙化颗粒数和钙化病灶直径以及钙化病灶直径与钙化颗粒大小及密度是否均匀等方面具有差异性,更好地帮助医师对其进行鉴别诊断,应用价值高,值得应用推广。
Objective To investigate the value of mammography X-ray microcalcification in the diagnosis of negative breast disease by color Doppler ultrasonography. Methods 85 cases of microcalcifications found by preoperative molybdenum target in Zhuhai Maternal and Child Health Hospital from January 2010 to August 2015 were enrolled in this study. All patients underwent X-ray and high-frequency color Doppler ultrasonography. X-ray examination Calcification and pathological results were compared to observe its clinical value. Results Among the 85 patients, 45 cases were benign (including 25 cases of breast disease, 15 cases of breast fibroadenoma and 5 cases of atypical ductal hyperplasia), accounting for 52.9%. Malignant lesions in 40 cases (mainly including 20 cases of invasive ductal carcinoma, ductal carcinoma in situ in 12 cases, lobular carcinoma in situ in 5 cases, invasive lobular carcinoma in situ in 3 cases), accounting for 47.1%. Clustered calcification of benign breast lesions and benign lesions Clustered calcifications in the number of calcifications, calcification points, calcification density, calcification in each cluster calcification number and diameter of calcified lesion and calcified lesion diameter and size and density of calcified particles were compared There was statistical significance (P <0.05). Conclusion The clinical application of mammography on the detection of microcalcifications has the good effect on the diagnosis of negative early breast cancer by color Doppler ultrasonography. In particular, the number of calcifications, the number of calcifications and the density of calcification in benign and malignant lesions of microcalcification, Clustered calcification calcification in the number of particles and calcification lesions diameter and calcified lesion diameter and calcification particle size and density are uniform and so on are different, to better help the doctor to differentiate its diagnosis, high value, it is worth to promote the application.