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金霉素是酸碱双性化合物;可因溶剂PH的不同变成金霉素钠盐或盐酸金霉素,普通临床(内服或注射)应用的为其盐酸化合物,呈酸性。其溶解度随溶剂的PH及加入其他的缓冲剂而变化,溶剂愈倾向碱性溶解度也增加,但亦易于失效。临床应用金霉素的治疗剂量时可发生各种反应,但大部都轻微,停药后迅速恢复,一般最常见的为消化道反应(尤以口服者多见)。长期应用可发生维生素B族缺乏症或
Chlortetracycline is a bifunctional acid-base compound; due to different solvent PH into chlortetracycline sodium or chlortetracycline hydrochloride, the general clinical (oral or injection) for its hydrochloric acid compounds, acidic. The solubility varies with the pH of the solvent and by the addition of other buffers. The more solvent tends to have an increased alkaline solubility, but it also tends to fail. Clinical application of chlortetracycline dose can occur when a variety of reactions, but most are mild, rapid recovery after stopping the drug, the most common is the most common gastrointestinal reactions (especially oral more common). Long-term use can occur vitamin B family deficiency or