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目的 探讨吉兰 巴雷 (Guillain Barr啨)综合征 (GBS)的电生理学分型及不同电生理亚型的发病特点。方法 回顾分析我院近 2 0年诊断的 10 0例GBS病人的电生理和临床资料 ,应用 χ2 检验比较不同年龄阶段GBS各亚型发病的差异性。结果 10 0例GBS病人中原发性脱髓鞘型 5 1例 ,原发性轴索型 2 5例 ,神经失电位型 8例 ,不明确型 12例 ,正常型 4例。在不同年龄阶段起病的GBS以及在不同病程阶段检测均以脱髓鞘型为主要形式 ,各年龄组之间GBS亚型构成比差异无显著性意义。GBS病人中病前 32 .0 %患上呼吸道感染 ,2 2 .0 %患消化道感染。农村和城市病例数几乎各占一半 ,未见有明显的城乡分布差异。脱髓鞘型和轴索型GBS全年均有新发病人 ,第三季度发病人数相对为多。结论 在我院就诊的 10 0例GBS病人的主要发病形式是原发性脱髓鞘型 ,各亚型的发病特点与欧美以及河北医学院第二附属医院的结果比较均存在一定的差异。
Objective To investigate the electrophysiological classification of Guillain Barr’s syndrome (GBS) and the incidence of different electrophysiological subtypes. Methods The electrophysiological and clinical data of 100 GBS patients diagnosed in our hospital in recent 20 years were retrospectively analyzed. The differences of the incidence of GBS subtypes in different age groups were compared by Chi-square test. Results Among 100 GBS patients, 51 cases were primary demyelination, 25 cases were primary axon, 8 cases were neural loss potentials, 12 cases were unidentified and 4 cases were normal. The onset of GBS in different age groups and in different stages of the disease were demyelinated as the main form of GBS subtypes between the age groups the composition ratio was not significant. In GBS patients, 32.0% of the patients had respiratory tract infections and 22.0% had digestive tract infections. Almost half of the cases in rural areas and urban areas do not show obvious differences in urban-rural distribution. Demyelinating and axonal GBS new onset all year round, the third quarter, the incidence of relatively much. Conclusion The main pathogenesis of 100 cases of GBS patients treated in our hospital is primary demyelination. The characteristics of each subtype are different from those of Europe and the United States and the Second Affiliated Hospital of Hebei Medical University.