论文部分内容阅读
用放免法测定４４例肝硬化及其合并有慢性浅表性胃炎（ＣＳＧ）、消化性溃疡（ＰＵ）患者血浆胃动素水平，并据Ｃｈｉｌｄ－ｐｕｇｈ法分Ａ、Ｂ、Ｃ级肝功能进行比较。结果肝硬化组胃动奈明显高于对照组（５０９±１６２．２μｇ／Ｌ比３０６±２８．６μｇ／Ｌ，ｐ＜０．０１），胃动素水平与肝功能损害程度成正比。肝病时，胃动素代谢及灭活障碍及肾脏功能损害均可导致血浆胃动素增高。测定肝硬化患者血浆胃动素含量可作为临床判定肝功能损害程度的指标之一。
Forty-four patients with liver cirrhosis and those with chronic superficial gastritis (CSG) and peptic ulcer (PU) were measured by radioimmunoassay. Plasma motilin levels were determined according to Child-pugh test grade A, B and C liver function Compare Results The gastric motility in liver cirrhosis group was significantly higher than that in control group (509 ± 162.2 μg / L vs 306 ± 28.6 μg / L, p <0.01). Motilin level was directly proportional to the extent of liver dysfunction. Liver disease, motilin metabolism and inactivation disorders and renal dysfunction can lead to increased plasma motilin. Determination of plasma motilin levels in patients with cirrhosis can be used as clinical indicators of liver damage one of the indicators.