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自Hamberg和Moncada发现血小板和血管壁前列腺素代谢可产生两种作用完全相反的物质—TXA_2和PGI_2后,许多学者注意到它们在动脉粥样硬化(AS)形成中的作用,认为AS的发生是由于
Since Hamberg and Moncada found that platelets and vascular wall prostaglandin metabolism produce two oppositely acting substances, TXA_2 and PGI_2, many scholars have noticed their role in the development of atherosclerosis (AS). They think that the occurrence of AS is due to