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在研究5-羟色胺2A受体基因多态性与精神分裂症的关联分析中,调查了202例精神分裂症患者及202例正常对照。各相匹配组间比较未发现基因型和等位基因频率的显著性差异。结果提示,在中国人群中5-羟色胺2A受体的静态T102C突变与精神分裂症之间不存在关联。
In a study to correlate the serotonin 2A receptor gene polymorphism with schizophrenia, 202 schizophrenia patients and 202 normal controls were investigated. Significant differences in genotype and allele frequencies were not found between the matched groups. The results suggest that there is no association between the static T102C mutation of serotonin 2A receptors and schizophrenia in the Chinese population.