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目的：测定６３例缺铁性贫血（ＩＤＡ）合并反复呼吸道感染（ＲＲＩ）患儿外周血白细胞介素２（ＩＬ－２）活性、血清可溶性白细胞介素２受体（ｓＩＬ－２Ｒ）水平和Ｔ淋巴细胞亚群，并分析它们之间的相关性。方法：ＩＬ－２活性和ｓＩＬ－２Ｒ水平测定分别采用ＭＴＴ法和双抗体夹心法，Ｔ淋巴细胞亚群测定采用ＡＰＡＡＰ法。结果：ＩＬ－２活性，ＣＤ３＋、ＣＤ４＋细胞百分率和ＣＤ４＋／ＣＤ８＋细胞比值均显著低于对照组（Ｐ均＜０．０１），而ｓＩＬ－２Ｒ水平显著高于对照组（Ｐ＜０．０１），ＣＤ８＋细胞百分率无明显变化。结论：ＩＤＡ合并ＲＲＩ患儿细胞免疫功能低下且紊乱。
Objective: To determine the levels of interleukin-2 (IL-2), soluble interleukin 2 receptor (sIL-2R) and T lymphocyte subsets in 63 children with iron deficiency anemia (IDA) and recurrent respiratory tract infection Lymphocyte subsets, and analyze the correlation between them. Methods: The levels of IL-2 and sIL-2R were determined by MTT assay and double antibody sandwich assay, respectively. The T lymphocyte subsets were assayed by APAAP assay. Results: The levels of IL-2, CD3 +, CD4 + cells and CD4 + / CD8 + cells were significantly lower than those of the control group (all P <0.01), while the levels of sIL-2R were significantly higher than those of the control group , No significant changes in the percentage of CD8 + cells. Conclusion: Children with IDA and RRI have poor cellular immune function and disorder.