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目的;探讨胆囊炎、胆结石患者肝脏病理变化。方法;94例临床无肝功异常表现和体征的胆囊炎、胆结石患者,在胆囊切除术中进行肝活检,光镜下观察肝脏病理变化。结果:94例胆囊炎、胆囊结石患者中,肝组织正常者35例(37.2%),异常者59例(62.8%)。异常病理变化包括肝组织内炎细胞浸润,肝细胞胞浆疏松化,肝细胞脂肪变性,肝纤维化,肝组织胆汁淤积。结论:胆囊炎、胆结石与肝脏病理变化有关,术前进行有关肝脂肪变性肝纤维化的血清学检查,必要时术中进行肝活检。
Objective To investigate the pathological changes of liver in patients with cholecystitis and gallstones. Methods Ninety-four patients with cholecystitis and gallstones who had no clinical manifestations and signs of liver dysfunction were subjected to liver biopsy under cholecystectomy and pathological changes of liver were observed under light microscope. Results: Of the 94 patients with cholecystitis and cholecystolithiasis, 35 (37.2%) had normal liver tissue and 59 (62.8%) had abnormal liver tissue. Abnormal pathological changes include infiltration of inflammatory cells in liver tissue, loosening of cytoplasm of liver cells, steatosis of liver cells, liver fibrosis, and cholestasis of liver tissue. Conclusions: Cholecystitis and gallstones are related to the pathological changes of liver. Serological tests on hepatic steatosis and hepatic fibrosis are performed preoperatively and intraoperative liver biopsy is performed if necessary.