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颅内原发性黑色素瘤是极为少见的恶性肿瘤,一般具有恶性程度高,病程短,发展快,无典型临床表现,诊断治疗困难等特点。Bouton1958年统计近百年的文献中能查到的原发性黑色素瘤仅66例。Pappenheim等收集美国及欧洲百年文献发现颅内原发性黑色素瘤34例。松本正六等收集日本文献中颅内原发性黑色素瘤11例。据国内1955～1980年收集到的文献中颅内原发性黑色素瘤共10例。李荣基等报告颅内原发性黑色素瘤4例,占同期肿瘤的0.5%。丁育基报告了3例,占颅内肿瘤总例数的0.07%。我院经病理证实的颅内肿瘤1359例中,原发性黑色素瘤3例,占肿瘤总例数的0.22%。兹将我院3例报告如下:
Intracranial primary melanoma is a very rare malignant tumor, usually with a high degree of malignancy, short course, rapid development, no typical clinical manifestations, diagnosis and treatment difficulties and so on. Sixty-six cases of adverse reactions were reported by Bouton in 1985. Pappenheim and other collected hundreds of years of literature in the United States and Europe found 34 cases of intracranial primary melanoma. Matsumoto positive sixth collection of Japanese literature intracranial primary melanoma in 11 cases. According to the domestic literature collected from 1955 to 1980 in 10 cases of primary intracranial melanoma. Li Rongji and other reports of intracranial primary melanoma in 4 cases, accounting for 0.5% of the same period tumors. Ding Yuji reported 3 cases, accounting for 0.07% of the total number of intracranial tumors. 1359 cases of pathologically confirmed intracranial tumors in our hospital, 3 cases of primary melanoma, accounting for 0.22% of the total number of tumors. Here are 3 cases of our hospital report as follows: