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结直肠癌是欧美国家最常见的癌肿之一。早期癌和腺瘤样癌前病变常常可以通过内镜进行息肉切除或粘膜切除而得到治愈。与较常见的息肉样腺瘤相比,平坦型腺瘤和凹陷性早期癌即使病灶很小,但是粘膜下侵润的比例已相当高。因此,常规结肠镜检查的目标是检出和切除癌前期病变和早期癌。日本研究人员已证明染色内镜对这类病变的检出和分类有帮助。靛青红是最常用的染色剂,能清晰显示肠粘膜的浅表结构,深蓝颜色充填到平坦溃疡的缝隙、糜烂灶和皱襞,能提高平坦型和凹陷型癌以及其他异常隐窝的观察。这项技术也是鉴别结肠增生性病变和腺瘤样肿瘤的“凹陷型分类”的基础。此研究旨在评价染色内镜在常规结肠镜检查中的应用价值。
Colorectal cancer is one of the most common cancers in Europe and the United States. Early cancers and adenomatous carcinomas can often be cured by endoscopic polypectomy or mucosal resection. In contrast to the more common polypoid adenomas, the proportion of submucosal infiltrates is fairly high even for flat adenomas and depressed early carcinomas, even if the lesions are small. Therefore, the goal of routine colonoscopy is to detect and excise precancerous lesions and early cancers. Japanese researchers have demonstrated that staining endoscopy is helpful in the detection and classification of such lesions. Indigo red is the most commonly used staining agent, can clearly show the superficial structure of the intestinal mucosa, dark blue color filled into the flat ulcer gap, erosion and folds, can improve the flat and concave cancer and other abnormal crypt observation. This technique is also the basis for the identification of “recessive” colon biopsy and adenoid tumors. The aim of this study was to evaluate the value of stained endoscopy in routine colonoscopy.