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本世纪初就有性器官先天发育缺欠患者易发癌症的报道。近年研究进一步证实,在这类患者中,以XY型性腺发育不全(XY gonadal dysgenesis简称XYGD)者最为突出,其发癌率高达30%—40%。现已查明,XYGD的发癌过程与性器官发育异常、遗传型、性别、年龄以及激素失调等很多方面,有着非常明显的联系。XYGD极易发生无性细胞瘤(dysgerminoma:DGN)和性母细胞瘤
The beginning of this century there is a lack of congenital defects in sexual organs in patients with cancer reports. In recent years, studies further confirmed that in these patients, with XY gonadal dysgenesis (XYGD referred to as the most prominent, the incidence of cancer as high as 30% -40%. It has been identified, XYGD cancer process and sexual organ development, genetic type, gender, age and hormone disorders and many other aspects, has a very obvious connection. XYGD prone to dysgerminoma (dysgerminoma: DGN) and the blastoma