心脏MRI检查孤立性单支肺静脉异位连接的生理学特征

• 作 者: Dyme J.L. Prakash A. Printz B.F. J.C. Nielsen 黄浙勇
• 机 构: Division of Pediatric Cardiology Mount Sinai School of Medicine New York NY United States Dr. ,
• 出 处: 世界核心医学期刊文摘(心脏病学分册)
• 发表日期: 2006年11期
• 关键词: 异位 心脏 生理学特征 左向右分流 舒张末容积 正常值上限 立性 异常肺静脉 房间隔缺损 循环血流量

The physiology of isolated partially anomalous pulmonary venous connection of a single pulmonary vein has yet to be fully characterized. This study assessed the magnitude of the left-to-right shunt and right ventricular(RV) dilation from a single anomalous pulmonary vein using cardiac magnetic resonance imaging. Subjects with >1 anomalous pulmonary vein or associated lesions, including atrial septal defects, were excluded. In the 6 subjects identified, the median pulmonary-to-systemic flow ratio was 1.55(range 1.3 to 1.6). The mean RV end-diastolic volume indexed to body surface area in the subjects was significantly larger than in a normal reference cohort(108±16 vs 78±18 cm3/m2, p=0.0009) and greater than the upper limit of normal in all 6 subjects. Older age did not correlate with increased magnitude of shunting(r=0.3, p=0.5), but increased age did correlate with RV end-diastolic volume indexed to body surface area(r=0.96, p=0.01). Isolated partially anomalous pulmonary venous connection with only 1 vein connecting anomalously results in a modest left-to-right shunt and mild RV dilation.

The physiology of isolated partially anomalous pulmonary venous connection of a single pulmonary vein has yet to be fully characterized. This study assessed the magnitude of the left-to-right shunt and right ventricular (RV) dilation from a single anomalous pulmonary vein using cardiac magnetic Of the 6 subjects identified, the median pulmonary-to-systemic flow ratio was 1.55 (range 1.3 to 1.6). The mean RV end -diastolic volume indexed to body surface area in the subjects was significantly larger than in a normal reference cohort (108 ± 16 vs 78 ± 18 cm3 / m2, p = 0.0009) and greater than the upper limit of normal in all 6 subjects. Older age did not correlate with increased magnitude of shunting (r = 0.3, p = 0.5) but increased age did correlate with RV end-diastolic volume indexed to body surface area (r = 0.96, p = 0.01) con nection with only 1 vein connecting anomalously results in a modest left-to-right shunt and mild RV dilation.