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目的探讨引起新生儿失血性贫血的相关临床因素及临床特点。方法对我院2004—2008年收治的新生儿失血性贫血病例资料进行分析。结果 123例新生儿失血性贫血中,以早期新生儿贫血(发病日龄<7天)为主,共118例(95.9%),其中<3天的新生儿95例,占80.5%。新生儿失血性贫血的病因及相关因素主要有胎-母输血69例(56.1%),新生儿颅内出血11例(8.9%),新生儿出血症8例(6.5%),胎胎输血综合征8例(6.5%)。新生儿失血性贫血以重度失血(56.1%)多见(P<0.05),不同性别差异无统计学意义。胎胎输血以早产儿为主。结论新生儿失血性贫血中胎-母输血为主要原因,其次为新生儿颅内出血、新生儿出血症、胎胎输血综合征等;新生儿重度贫血发生率较高,足月儿与早产儿发生贫血的原因有所不同。
Objective To investigate the related clinical factors and clinical features of neonates with hemorrhagic anemia. Methods The data of neonates with hemorrhagic anemia admitted in our hospital from 2004 to 2008 were analyzed. Results Among the 123 cases of neonatal hemorrhagic anemia, there were 118 cases (95.9%) with early neonatal anemia (onset day <7 days), of which 95 cases (80.5%) were newborn infants <3 days. The causes of neonatal hemorrhagic anemia and related factors are the fetal-maternal blood transfusion in 69 cases (56.1%), neonatal intracranial hemorrhage in 11 cases (8.9%), neonatal bleeding in 8 cases (6.5%), fetal transfusion syndrome 8 cases (6.5%). Neonatal hemorrhagic anemia with severe bleeding (56.1%) more common (P <0.05), gender differences were not statistically significant. Tire blood transfusions to premature children. Conclusions Fetal-maternal blood transfusion is the main cause of neonatal hemorrhagic anemia, followed by neonatal intracranial hemorrhage, neonatal hemorrhagic disease, fetal blood transfusion syndrome, etc. The incidence of severe anemia in newborns is high, and full-term infants and premature infants occur The cause of anemia is different.