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目的探讨女性宫颈与盆腔解脲支原体(UU)感染与输卵管性不孕的关系及其感染特点,探讨腹腔镜手术在输卵管性不孕的诊断中的作用。方法应用聚合酶链反应(PCR)方法对经腹腔镜检查确诊的输卵管性不孕患者(不孕组36例)和因卵巢肿瘤等原因而行腹腔镜手术、有正常生育史的患者(对照组23例)进行宫颈分泌物和盆腔液体的UU检测,并通过腹腔镜观察盆腔粘连情况,在腹腔镜下行美兰通液观察输卵管通畅程度。结果1.不孕组与对照组宫颈分泌物的UU阳性率分别为30.6%(11/36)和8.7%(2/23),两者相比有显著性差异(P<0.05);两组患者盆腔液体UU阳性率分别为5.6%(2/36)和0%(0/23),二者无显著性差异(P>0.05);2.不孕组中UU阳性患者输卵管阻塞率为87.5%,明显高于同组UU阴性患者输卵管阻塞率64.6%(P<0.05);在两组共59例患者中,UU阳性患者中仅14.3%有盆腔炎症状,与无UU感染的患者相比无显著性差异(P>0.05);3.不孕组中UU阳性者输卵管粘连以无粘连或轻度粘连为主,占50%(12/24条输卵管);UU阴性者则以中、重度粘连为主,占79.2%(38/48条输卵管),两者比较有显著性差异(P<0.05)。结论1.女性生殖道UU感染与输卵管性不孕相关;2.UU感染症状隐匿,多数患者无明显临床症状,但输卵管腔损害明显;3.早期腹腔镜检查对怀疑感染所致的不孕症患者有必要;4.不
Objective To investigate the relationship between cervical and pelvic UU infection and tubal infertility, and to explore the role of laparoscopic surgery in the diagnosis of tubal infertility. Methods Polymerase chain reaction (PCR) was performed on patients with tubal infertility confirmed by laparoscopy (36 cases of infertility group) and patients undergoing laparoscopic surgery due to ovarian cancer, and with normal fertility history (control group 23 cases) for cervical secretion and pelvic fluid UU detection, and pelvic adhesions observed by laparoscopy, laparoscopic melanin pass observation tubal patency. The positive rates of UU in cervical secretions of infertility group and control group were 30.6% (11/36) and 8.7% (2/23) respectively, there was a significant difference (P <0.05) between the two groups The positive rate of UU in pelvic fluid of patients was 5.6% (2/36) and 0% (0/23) respectively, with no significant difference (P> 0.05). 2. The tubal obstruction rate of UU positive patients in infertility group was 87.5 %, Which was significantly higher than that of UU-negative patients in the same group (64.6%, P <0.05). In 59 of the 59 patients in both groups, only 14.3% of UU-positive patients had pelvic inflammatory symptoms compared with those without UU infection There was no significant difference (P> 0.05). 3. In the infertility group, UU-positive tubal adhesions were mainly associated with no adhesions or mild adhesions, accounting for 50% (12/24 tubal); those with UU negative were moderate and severe Adhesion, accounting for 79.2% (38/48 tubal), the two were significantly different (P <0.05). UU infection of female genital tract is associated with tubal infertility; 2.UU infection occult symptoms, most patients have no obvious clinical symptoms, but tubal cavity damage is obvious; 3. Early laparoscopy infertility caused by suspected infection Patients are necessary; 4