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目的探讨早孕期胎盘容积及其血管化参数预测复发性流产者妊娠结局的价值。方法将优生遗传门诊就诊同时自愿进行三维能量多普勒超声测量的孕妇51例分为两组,研究组30例为复发性流产孕妇,对照组21例为正常妊娠孕妇,在早孕期使用三维能量多普勒超声胎盘容积及VI、FI、VFI测量,将两组孕妇所得的数据进行统计学分析比较。结果观察组孕妇早孕期胎盘容积及血管化指数VI、VFI显著低于对照组孕妇,差异有统计学意义(P<0.05),两组孕妇FI差异无统计学意义(P>0.05)。妊娠早期胎盘容积、胎盘血流VI、FI、VFI做为预测持续妊娠≥12周指标的ROC曲线下面积分别为0.771、0.907、0.592、0.771,FI的预测准确度较低,胎盘容积、VFI有一定准确度,VI有较高准确度。结论早孕期胎盘的VI对预测复发性流产者妊娠结局最为敏感,三维能量多普勒在复发性流产监测中有较好的应用价值。
Objective To investigate the value of placental volume and its vascularization parameters in early pregnancy to predict pregnancy outcome in recurrent spontaneous abortion. Methods 51 pregnant women who were diagnosed by eugenics and outpatient voluntarily by three-dimensional energy Doppler ultrasound were divided into two groups. The study group consisted of 30 pregnant women with recurrent spontaneous abortion and 21 healthy pregnant women with normal pregnancy. In the first trimester, three-dimensional energy Doppler ultrasound placental volume and VI, FI, VFI measurements, the data obtained from two groups of pregnant women for statistical analysis and comparison. Results The placental volume and vascularization index of pregnant women in the first trimester of pregnancy were significantly lower than those of the control group (P <0.05). There was no significant difference in FI between the two groups (P> 0.05). The area under the ROC curve of placental volume, placental blood flow volume VI, FI and VFI in the first trimester was 0.771, 0.907, 0.592 and 0.771, respectively. The accuracy of FI was lower than that of the control group. The placental volume, VFI A certain accuracy, VI has a higher accuracy. Conclusion The first trimester placenta is most sensitive to predicting pregnancy outcome in recurrent spontaneous abortion, and the three-dimensional energy Doppler has good value in the monitoring of recurrent spontaneous abortion.