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[目的]探索跟随载荷对多节段颈椎弯矩-转角参数及椎间盘内压的影响.[方法]用六轴机器人完成15具新鲜冷冻人颈椎标本(C3-7)的前屈、后伸运动,目标纯扭矩为2.0 Nm,分为无压缩载荷组和跟随载荷组.记录ROM与IDP,中性区参数由基于弯矩-转角曲线的双“S”拟合函数计算获得.[结果]跟随载荷的应用显著减少C3/7的ROM,增加中性区的刚度,但对中性区的宽度和屈曲与后伸方向的弹性区刚度没有影响.标本在中立位加载跟随载荷时C3/4与C6/7椎间隙的IDP值均在应用跟随载荷后显著增加,且与跟随载荷值显著相关.跟随载荷显著增加前屈运动过程中C3/4和C6/7IDP的增加幅度,降低后伸运动过程中C3/4IDP的增加幅度及C6/7的IDP值.[结论]跟随载荷的应用能增加中性区的刚度,减少标本的ROM,增加颈椎的稳定性.“,”[Objective] To explore effect of follower load on multi-segment cervical spine moment-rotation parameters and intradiscal pressure.[Methods] Fifteen fresh-frozen human (C3-7) cervical specimens were biomechanically tested in a 6-DOF system robot for a pure moment target of 2.0 Nm in flexion and extension,which were divided into two groups,the no compression group and the follower load group.Range of motion and intradiscal pressure were recorded.Neutral zone parameters were calculated based on the moment-rotation curve using a double sigmoidal function.[Results] Application of follower load significantly decreased C3-7 ROM,increased neutral zone stiffness,but resulted in no change in the neutral zone width or elastic zone stiffness.C3/4 and C6/7 IDP measured in the neutral position was significantly increased as follower load applied,with a correlation between them.The follower load increased the IDP change of C3/4 and C6/7 during flexion,whereas decreased the IDP change of C3/4 and C6/7 during extension.[Conclusion] Application of follower load significantly decreases ROM of the cervical specimen,accompanied with increased neutral zone stiffness and increased the stability of specimen.