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目的探讨慢性阻塞性肺疾病合并呼吸衰竭应用无创正压通气治疗的临床疗效。方法 80例慢性阻塞性肺疾病合并呼吸衰竭患者,随机分为观察组和对照组,每组40例,对照组患者应用常规治疗,观察组在对照组治疗的基础上给予无创正压通气治疗,对比分析两组患者治疗前后呼吸频率、心率、动脉血氧分压(Pa O2)、动脉血二氧化碳分压(Pa CO2)、p H值。结果治疗前两组患者心率、呼吸频率、Pa CO2、Pa O2、p H值比较差异无统计学意义(P>0.05),治疗后观察组患者心率、呼吸频率、Pa CO2、Pa O2、p H值均明显优于对照组(P<0.05)。结论无创正压通气治疗慢性阻塞性肺疾病合并呼吸衰竭疗效确切,可有效的改善患者的临床症状,阻止病情发展,有助于呼吸衰竭的纠正,值得临床推广和应用。
Objective To investigate the clinical efficacy of non-invasive positive pressure ventilation in patients with chronic obstructive pulmonary disease (COPD) complicated with respiratory failure. Methods Eighty patients with chronic obstructive pulmonary disease and respiratory failure were randomly divided into observation group and control group, 40 cases in each group. Patients in control group were treated with conventional therapy. Observation group was given non-invasive positive pressure ventilation on the basis of the control group, The respiratory rate, heart rate, arterial oxygen tension (Pa O2), arterial carbon dioxide partial pressure (Pa CO2) and p H before and after treatment were compared between the two groups. Results There was no significant difference in heart rate, respiratory rate, PaCO 2, Pa 2 O, and p H between the two groups before treatment (P> 0.05). After treatment, heart rate, respiration rate, PaCO 2, Values were significantly better than the control group (P <0.05). Conclusion Noninvasive positive pressure ventilation is effective in treating chronic obstructive pulmonary disease combined with respiratory failure, which can effectively improve the clinical symptoms, prevent the progression of the disease and help to correct respiratory failure, which is worthy of clinical promotion and application.