论文部分内容阅读
目的研究脑桥梗死的危险因素、临床表现、神经影像学改变及预后。方法回顾性分析100例脑桥梗死患者的临床资料,包括:高危因素、临床表现、影像学检查及预后。结果高危因素:高脂血症、高血压、糖尿病、吸烟。主要病因为动脉粥样硬化。主要临床特点:眩晕、病灶对侧的中枢性面瘫和肢体瘫痪、构音障碍、偏身麻木、球麻痹、眼震、复视、意识障碍等。按照头颅磁共振成像(MRI)横轴位上的病灶位置,腹内侧梗死49例,腹外侧梗死31例,被盖部梗死13例,双侧梗死7例。腹内、外侧梗死起病后30 d后神经功能缺失症状较前好转,差异具有统计学意义(P<0.01)。双侧脑桥梗死改良Rankin量表(m RS)评分较其余各组高,差异具有统计学意义(P<0.05)。结论动脉粥样硬化是脑桥梗死患者最常见的病因,眩晕、感觉运动障碍、构音障碍、球麻痹是常见的临床特点,脑桥梗死病灶多位于腹侧,不同部位范围影响患者预后。
Objective To study the risk factors, clinical manifestations, neuroimaging and prognosis of pontine infarction. Methods The clinical data of 100 patients with pontine infarction were retrospectively analyzed, including the risk factors, clinical manifestations, imaging findings and prognosis. High risk factors: hyperlipidemia, hypertension, diabetes, smoking. The main cause is atherosclerosis. Main clinical features: vertigo, contralateral central paralysis and limb paralysis, dysarthria, partial numbness, ball paralysis, nystagmus, diplopia, disturbance of consciousness. According to the location of lesion on the transverse axis of cranial magnetic resonance imaging (MRI), there were 49 cases of abdominal ventral infarction and 31 cases of abdominal ventral infarction. Thirteen cases were occluded lidded and 7 cases had bilateral infarction. The symptoms of neurological deficits improved after 30 d after onset of intra-abdominal and lateral infarction, with statistical significance (P <0.01). Bilateral pontine infarction improved Rankin Scale (m RS) score than the other groups, the difference was statistically significant (P <0.05). Conclusions Atherosclerosis is the most common cause of pontine infarction. Dizziness, sensory dyskinesia, dysarthria and ball paralysis are common clinical features. Most of the pontine lesions are located on the ventral side and the range of different parts affects the prognosis of patients.