论文部分内容阅读
自Ashbaugh(1967年)报道应用呼气末正压(PEEP)治疗急性呼吸衰竭(ARDS)始迄今已20余年、大量临床实践表明其疗效显著,但也存在不少问题。Hall与Trim曾报道自主呼吸时应用PEEP可使心输出量(CO)显著减少,而动脉氧分压(PaO_2)却无明显增加。长期不适当应用PEEP可引起一系列心血管系血流动力学改变,继而导致其它脏器病理变化,甚至造成严重后果。本文仅就PEEP对心脏血流动力学的不良影
Since Ashbaugh (1967) reported that the application of positive end expiratory pressure (PEEP) for the treatment of acute respiratory failure (ARDS) has been more than 20 years so far, a large number of clinical practice shows that its efficacy is significant, but there are also many problems. Hall and Trim reported that application of PEEP during spontaneous breathing significantly reduced cardiac output (CO), whereas arterial oxygen pressure (PaO 2) did not increase significantly. Long-term inappropriate use of PEEP can cause a series of cardiovascular hemodynamic changes, which led to other organs pathological changes, and even cause serious consequences. This article only on the adverse effects of PEEP on hemodynamics