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药物引起过敏性血管炎是一种少见的并发症,已报道的药物有磺胺、硫脲嘧啶、大仑丁、metamphetamine及青霉素。作者报道1例用萘普生后发生皮肤坏死性血管炎、肾功能衰竭及肾病综合征的病例。患者男,52岁,因摩托车事故致左腿钝挫伤,口服萘普生(250mg,每12小时一次)和双氯青霉素(250mg,每6小时一次)。3日后发现双腿有斑丘疹,第4日停用双氯青霉素,继续不规则应用萘普生,许多皮疹成为水疱。3周后,因皮疹更为广泛、双臂出现新疹、面及足水肿而住
Drug-induced Allergic Vasculitis is a rare complication of drugs that have been reported to be sulfa, thiouracil, darundi, metamphetamine and penicillin. The authors report a case of skin necrotizing vasculitis, renal failure and nephrotic syndrome after naproxen. Male, 52, blunted left leg from motorcycle accident, taking naproxen (250 mg once every 12 hours) and dicloxacillin (250 mg every 6 hours). 3 days after the discovery of rash on both legs, dosing of dicloxacillin on the 4th, continue to irregular use of naproxen, many rashes into blisters. After 3 weeks, due to the rash is more widespread, new rash appears in his arms, face and foot edema and live