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199名早期诊断出 (发病期短于 2年 )的活动性ＲＡ病人 ,对其中的 99名联合用药 (柳氨磺胺吡啶Ｓｕｌｆａｓａｌａｚｉｎｅ,ＳＳＺ) 1ｇ/ｄ和甲氨蝶呤 (Ｍｅｔｈｏｔｒｅｘａｔｅ ,ＭＴＺ ) 7 5ｍｇ/周 ,羟氯喹 (Ｈｙｄｒｏｘｙｃｈｌｏｒｏｑｕｉｎｅ )30 0ｍｇ/ｄ和强的松龙 (
Ninety-nine active RA patients diagnosed early (with a disease onset of less than 2 years) were randomized to receive either 99 mg of sulfasalazine (SSZ) 1 g / d and methotrexate (MTZ) 75 mg / Week, hydroxychloroquine (Hydroxychloroquine) 30 0mg / d and prednisolone (