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目的:研究分析阿替普酶动脉溶栓治疗急性颈内动脉系统脑梗死的临床效果。方法:选取本院在2013年10月至2015年2月收治的68例急性颈内动脉系统脑梗死患者,按照治疗方法将其分为两组(各34例),观察组阿替普酶动脉溶栓治疗,对照组常规药物治疗,比较两组患者不同时间段美国国立卫生院卒中量表(NIHSS)评分、病死率和脑卒中再发率。结果:观察组患者治疗1个月后、治疗3个月后和治疗6个月后NIHSS评分均显著高于对照组患者和治疗前,病死率和脑卒中再发率均显著低于对照组患者,且并发症发生率8.8%显著低于对照组患者的29.4%,差异具有统计学意义(P<0.05)。结论:阿替普酶动脉溶栓治疗措施能有效改善急性颈内动脉系统脑梗死患者临床症状,降低病死率和再发脑卒中率。
Objective: To study the clinical effect of arterial thrombolysis with alteplase in the treatment of acute carotid artery cerebral infarction. Methods: Sixty-eight patients with acute carotid artery infarction admitted to our hospital from October 2013 to February 2015 were divided into two groups (34 in each group) according to the treatment method. The patients in the observation group were treated with alteplase Thrombolytic therapy and control group. The National Institutes of Health Stroke Scale (NIHSS) score, case fatality rate and stroke recurrence were compared between two groups at different time points. Results: The NIHSS scores of observation group were significantly higher than those of control group and before treatment, after 3 months of treatment and 6 months of treatment, the case fatality rate and stroke recurrence rate were significantly lower than those in control group , And the incidence of complications 8.8% was significantly lower than the control group 29.4%, the difference was statistically significant (P <0.05). Conclusion: Arterothrombolysis of arterial thrombolysis can effectively improve the clinical symptoms of patients with acute carotid artery cerebral infarction, reduce the mortality and recurrent stroke rate.