论文部分内容阅读
为了探究血流动力学性能对再狭窄的影响,本文介绍了一种基于圆柱形内壁模型的血管支架耦合系统血流动力学性能的测试方法,并根据此方法自行设计并搭建一套实验装置,通过此装置对本实验室自制的冠脉支架进行了血流动力学性能测试实验。实验在脉动流下进行,实验结果表明,一个脉动周期内,靠近壁面的粒子运动速度先增大后减小,且速度总体数值很小;在同一时刻随着离壁面距离的增大,速度一直呈递增的趋势;在距离壁面同一位置处,速度随时间先增大后趋于平缓,在周期末尾时急剧下降到零,并伴有回流现象。通过计算壁面剪应力发现,一个周期内,壁面剪应力随时间变化先增大后减小;低于0.4Pa的时间占整个周期的一半,且分布在周期的开端和末端,是容易发生再狭窄的时间区分布。本实验对后续血流动力学性能测量提供了一定的实验基础,并且对后期支架的设计和优化提供了验证的手段。
In order to explore the influence of hemodynamic performance on restenosis, this paper introduces a method for testing the hemodynamic performance of a vascular stent-coupled system based on a cylindrical inner wall model. According to this method, a set of experimental apparatus is designed and set up by itself, Through this device, the self-made coronary stent in our laboratory was tested on the hemodynamic performance. The experimental results show that the velocity of the particle near the wall first increases and then decreases, and the velocity is small in a pulsating cycle. The velocity of the particle increases with the distance from the wall at the same time Increasing trend; at the same position away from the wall, the velocity first increases and then becomes gentle with time, sharply drops to zero at the end of the cycle, accompanied by reflux. By calculating the wall shear stress, it is found that the wall shear stress first increases and then decreases with time in one cycle; the time less than 0.4 Pa takes up half of the whole cycle and is distributed at the beginning and end of the cycle, which is prone to restenosis The time zone distribution. This experiment provides some experimental basis for the follow-up hemodynamic performance measurement, and provides a means of verification for the design and optimization of the post-stent.