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目的调查研究舟山地区孕妇及新生儿汞暴露现状,为相关防治措施的制定提供科学依据。方法选择2006年3月～2007年7月在舟山市妇幼保健医院分娩的舟山本地户籍孕妇及其新生儿作为本次研究对象,对孕妇尿、血、头发及其新生儿脐带血进行汞含量测定,并进行书面问卷调查。结果本研究共测定孕妇尿汞样2 190份,算术平均值为2.58μg/L;发汞3 109份,算术平均值为1.27 mg/kg;血汞3 337份,算术平均值为5.40μg/L;新生儿脐带血汞样本2 998份,算术平均值为7.71μg/L;获得孕妇尿汞、发汞、血汞及新生儿脐带血汞相对应样本及问卷1 554份,研究显示孕妇的尿汞值、发汞值、血汞值、新生儿脐血汞值存在关联性,其中孕妇血汞值与脐血汞值关联性最强(r=0.600,P<0.01),其他的相关系数均小于0.20。孕妇吃鱼次数与尿汞、血汞和新生儿脐带血汞水平相关。结论舟山地区孕妇尿、血和脐带血汞量与孕妇吃鱼次数有关,有很大比例的孕妇和新生儿有潜在的汞危害,需要进一步采取措施进行干预。
Objective To investigate the status of mercury exposure in pregnant women and newborns in Zhoushan, and provide scientific basis for the establishment of relevant prevention and treatment measures. Methods From March 2006 to July 2007, Zhoushan Maternal and Child Health Hospital in Zhoushan, the local census of pregnant women and their newborns as the research object, pregnant women urine, blood, hair and neonatal umbilical cord blood mercury determination , And conducted a written questionnaire. Results In this study, 2 190 urinary mercury samples from pregnant women were assayed with an arithmetic mean of 2.58 μg / L; 3 109 were made of mercury, with an arithmetic mean of 1.27 mg / kg; 3 337 blood mercury samples with an arithmetic mean of 5.40 μg / L; neonatal umbilical cord blood mercury samples 2 998 copies, the arithmetic mean of 7.71μg / L; obtained urine mercury, hair mercury, blood mercury and neonatal umbilical cord blood mercury samples and 1 554 questionnaires, studies have shown that pregnant women Urine mercury value, mercury value, blood mercury value, neonatal umbilical blood mercury value were correlated. Among them, blood mercury level of pregnant women had the highest correlation with umbilical blood mercury value (r = 0.600, P <0.01). Other correlation coefficients All less than 0.20. The frequency of pregnant women eating fish is associated with urinary mercury, blood mercury and neonatal umbilical cord blood mercury levels. Conclusion The blood levels of urinary, blood and umbilical cord blood of pregnant women in Zhoushan are related to the frequency of eating fish in pregnant women. A large proportion of pregnant women and newborns have potential mercury hazards and need further measures to intervene.